Science Advances

Supplementary Materials

This PDF file includes:

  • Table S1. Sequences of the human and mouse primers used for genotyping and qPCR.
  • Fig. S1. PlGF protein and mRNA expression levels in human and mouse cancer cell lines.
  • Fig. S2. Tumor growth, microvessel density, pericyte coverage, blood perfusion and leakiness, hypoxia, tumor cell proliferation, and apoptosis of Dll4-Notch inhibitor–treated PlGF tumors.
  • Fig. S3. TUNEL staining in each human and mouse tumor.
  • Fig. S4. Dll4-Notch inhibition–altered tumor growth and microvasculatures in mouse PlGF and PlGF+ tumors.
  • Fig. S5. Dll4-Notch inhibition–altered microvascular functions, tumor cell proliferation, and apoptosis in mouse PlGF and PlGF+ tumors.

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