Science Advances

Supplementary Materials

This PDF file includes:

  • Table S1. Physicochemical properties of cyproconazole and propiconazole.
  • Table S2. Measured concentrations of cyproconazole in exposure medium during the cell survival experiment (±SD): experiment 1, three technical replicates.
  • Table S3. Measured concentrations of cyproconazole in exposure medium during the cell survival experiment (±SD): experiment 2, three technical replicates.
  • Table S4. Measured concentrations of propiconazole in exposure medium during the cell survival experiment (±SD): experiment 1, three technical replicates.
  • Table S5. Measured concentrations of propiconazole in exposure medium during the cell survival experiment (±SD): experiment 2, three technical replicates.
  • Table S6. Measured concentrations of cyproconazole in exposure medium during cell proliferation experiments (0±SD) with three technical replicates per experiment.
  • Table S7. Measured concentrations of propiconazole in exposure medium during cell proliferation experiments (±SD) with three technical replicates per experiment.
  • Table S8. Parameters of the Hill slope equations for different time points (49).
  • Table S9. Estimates of GUTS-SD parameters for cell survival (in vitro) (lower/upper 95% confidence limit) (21, 50).
  • Table S10. Estimated parameters of the von Bertalanffy growth model.
  • Fig. S1. Survival fraction of RTgill-W1 cells exposed to a range of concentrations of the two pesticides over time.
  • Fig. S2. Proliferation of RTgill-W1 cells exposed to different cyproconazole concentrations (left column) and predicted reduction of fish weight caused by the respective concentration (right column: dashed lines represent the model uncertainty).
  • Fig. S3. Proliferation of RTgill-W1 cells exposed to different propiconazole concentrations (left column) and predicted reduction of fish weight caused by the respective concentration (right column: dashed lines represent the model uncertainty).

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