Science Advances

Supplementary Materials

This PDF file includes:

  • Materials and Methods
  • Fig. S1. Glycan symbolic representations of the fucosylated histo-blood group antigens that act as BabA receptors.
  • Fig. S2. Schematic illustration of the predicted domain structure of BabA.
  • Fig. S3. Alignment of BabA J99 and SabA 26695 protein sequences annotated with secondary structure elements.
  • Fig. S4. Superimposition of BabA from apo and cocrystal structures.
  • Fig. S5. Secondary structure and thermal stability of BabA and BabA variants.
  • Fig. S6. Type 1 and type 2 fucosylated histo-blood group antigen molecular models.
  • Fig. S7. Rainbow representation of apo-BabA.
  • Table S1. X-ray diffraction data collection and refinement statistics.
  • Table S2. Thermodynamic parameters of BabA:Leb interaction at pH 4.5 and 7.4.
  • Table S3. Binding affinity of BabA to various histo-blood group antigens.
  • Table S4. Oligonucleotides used in BabA cloning and site-directed mutagenesis.
  • References (6, 22, 46, 47)

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