Science Advances

Supplementary Materials

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  • Fig. S1. Mono-7D6-Fab bound to OT-I T cells does not alter antigen binding to the OT-I TCR.
  • Fig. S2. Mono-7D6-Fab increases T cell responses to weak antigens in vitro.
  • Fig. S3. Mono-7D6-Fab increases T cell IRF4 expression in response to weak antigens in vitro.
  • Fig. S4. CD4+ and CD8+ T cell subsets play a role in the anti-melanoma effects of Mono-7D6-Fab.
  • Fig. S5. Mono-7D6-Fab anti-melanoma metastasis effect requires T cells of relevant antigenic specificity or clone identity.
  • Fig. S6. Mono-7D6-Fab shows efficacy against pre-established metastases.
  • Fig. S7. Mono-7D6-Fab can increase Pmel-1 T cell response to mgp100 in vitro.
  • Fig. S8. TCR co-potentiation model.

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