Science Advances

Supplementary Materials

This PDF file includes:

  • Fig. S1. Sequence alignment and domain organization.
  • Fig. S2. Acetyl lysine binding site comparisons.
  • Fig. S3. Hydration thermodynamics of structural waters.
  • Fig. S4. DNA intercalation data of PFI-3.
  • Fig. S5. BLI data on the association of BRG1 with PFI-3.
  • Fig. S6. Characterization of the negative control compound.
  • Fig. S7. Stability of PFI-3 in cell culture medium.
  • Fig. S8. Transcription and chromatin modification of Brg1 target genes are affected by PFI-3.
  • Fig. S9. Gene set analysis.
  • Fig. S10. TSC differentiation is affected by inhibition or knockdown of members of the SWI/SNF complex.
  • Table S1. Temperature shift data for SA and PFI-3.
  • Table S2. ITC data for SA and PFI-3.
  • Table S3. Crystallographic data collection and refinement.
  • Table S4. CEREP screening data (GPCRs and enzymes).
  • Table S5. Significantly regulated genes.
  • Table S6. Primers used in ChIP.
  • Table S7. Primers used in qRT-PCR.
  • Table S8. Sequences of used miRNA.

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