Science Advances

Supplementary Materials

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  • fig. S1. LC-MS/MS detection of octopamine contents in worms.
  • fig. S2. TLC analysis of total lipids extracted from worms.
  • fig. S3. Overexpression of tbh-1 enhances lipid hydrolysis in well-fed wild-type worms.
  • fig. S4. Starvation does not alter the expression of atgl-1.
  • fig. S5. A mutation in tbh-1(n3247) does not affect the expression of fil-1 or fil-2 in starved worms.
  • fig. S6. Knockdown of lips-6 by RNAi leads to reduced lips-6 expression.
  • fig. S7. Overexpression of lips-6 in the intestine promotes lipid hydrolysis in well-fed WT worms.
  • fig. S8. Octopamine fails to restore lipid hydrolysis and expression of lips-6 in ser-3(ad1774) mutants during starvation.
  • fig. S9. SER-3 in the neurons and muscle is not involved in lipid hydrolysis during starvation.
  • fig. S10. SER-3 is involved in resistance to starvation.
  • table S1. ChIP-qPCR analysis of the tbh-1 promoter.

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