Science Advances

Supplementary Materials

This PDF file includes:

  • fig. S1. Expansion of the polyguanine repeat (G14 to G15) reduces the Ura3 protein abundance but not the mRNA level.
  • fig. S2. G11 to G14 sequences do not stop DNA polymerase from synthesizing DNA, whereas G-quadruplex does.
  • Legend for table S1
  • table S2. Chromosome insertion position and replication timing for engineered G14-URA inserts.
  • References (66, 67)

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Other Supplementary Material for this manuscript includes the following:

  • table S1 (Microsoft Excel format). Summary table of 318 sequenced ura3 mutants from G0, G14-ORF, and G14-repeat strains.

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