Science Advances

This PDF file includes:

• Supplementary Methods
• fig. S1. Analysis of 7q subtelomere.
• fig. S2. Control for TERRA-FISH in muscle biopsies.
• fig. S3. NRF1 is expressed in muscle biopsies.
• fig. S4. Time course of phenformin treatment in Huh-7 cells.
• fig. S5. Mutation of NRF1 binding sites in pGL3-10q construct.
• fig. S6. mPGC-1α overexpression in Huh-7 cells.
• fig. S7. Differentiated human myotubes.
• fig. S8. RNase control for TERRA-FISH in myotubes.
• table S1. Overview of available human subtelomeric sequences.
• table S2. Primers used in this study.
• table S3. Antibodies used in this study.
• References (41–45)

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