Science Advances

Supplementary Materials

This PDF file includes:

  • Supplementary Text
  • table S1. Summary of inhibitor action on SiNW internalization.
  • fig. S1. Perinuclear SiNW clustering.
  • fig. S2. SiNW tracking algorithm.
  • fig. S3. Stage drift controls.
  • fig. S4. Linear SiNW transport trajectories.
  • fig. S5. Migration coupled active transport.
  • fig. S6. Serum-free SiNW internalization.
  • fig. S7. Example MSD calculation.
  • fig. S8. Nocodazole-inhibited SiNW transport.
  • fig. S9. Active tug-of-war SiNW transport.
  • fig. S10. Lysosome tracking.
  • fig. S11. SiNW-cell colocalization determination.
  • fig. S12. Concentration-dependent metabolic activity assay.
  • fig. S13. Cell line–specific SiNW-cell colocalization.
  • fig. S14. Ensemble HUVEC control samples.
  • fig. S15. Multiple internalization events.
  • fig. S16. Chlorpromazine-positive control.
  • fig. S17. High-concentration A5 study.
  • fig. S18. Cytosolic SiNW protein sheath formation.
  • fig. S19. Prestained A5 SiNWs.
  • fig. S20. Lova inhibitor study.
  • Legends for movies S1 to S4

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Other Supplementary Material for this manuscript includes the following:

  • movie S1 (.mov format). Single-cell SiNW active transport.
  • movie S2 (.mov format). Bidirectional active tug-of-war SiNW transport.
  • movie S3 (.mov format). Macrophage internalization of SiNWs.
  • movie S4 (.mov format). SiNW membrane engulfment.

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