Science Advances

Supplementary Materials

This PDF file includes:

  • section S1. Previous work on homing endonuclease gene drives
  • section S2. Model for the evolutionary dynamics of a CRISPR gene drive with n gRNAs
  • section S3. Invasion of the drive construct
  • section S4. Stability of the drive construct
  • section S5. Interior equilibria
  • section S6. Numerical examples
  • section S7. Neutral resistance
  • fig. S1. Numerical simulations of the evolutionary dynamics.

Download PDF

Files in this Data Supplement: