Science Advances

Supplementary Materials

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  • fig. S1. Gross morphology of extrahepatic transplant sites during gel casting.
  • fig. S2. Correlation between site vascularization fractional area and site leukocyte density.
  • fig. S3. Blood glucose traces demonstrating individual recipient graft performance in extrahepatic islet transplant sites.
  • fig. S4. Long-term engraftment of marginal islet mass in EFP with PEG-VEGF.
  • fig. S5. Comparison of reversal in intraportal control islet transplant site and EFP/PEG-VEGF transplant site syngeneic diabetes reversal.
  • fig. S6. Survival curve for SUBQ groups.
  • fig. S7. Density of vascularized islets by site as demonstrated by lectin labeling.
  • fig. S8. Dose-dependent response of Luc+GFP+ islet signal in B6 recipients in EFP site over a 3-week period.
  • fig. S9. In vivo imaging of intraportally infused islets.
  • fig. S10. Bioluminescence signal kinetics by time point.
  • table S1. Exact P values for select comparisons between groups in vascularization metrics analyses.
  • table S2. Exact P values for select comparisons between groups in leukocyte presence analyses.

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