Science Advances

Supplementary Materials

This PDF file includes:

  • Supplementary Materials and Methods
  • table S1. Clinical characteristics of homozygous participants for the null SERPINE1 mutation.
  • table S2. Association of null SERPINE1 mutant allele status with PAI-1, telomere length, and fasting insulin: secondary analyses.
  • table S3. Association of cardiometabolic aging composite scores with 5-year CVD morbidity and mortality in the CARDIA cohort (n = 2793).
  • table S4. Association of biological aging composite scores including telomere length with 5-year CVD morbidity and mortality in the CARDIA cohort (n = 872).
  • fig. S1. Abbreviated pedigree of the Berne Amish kindred.

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