Science Advances

Supplementary Materials

  • This PDF file includes:
    • Fig. S1. Single spike–evoked Ca2+ rises in the second node of Ranvier drive AP narrowing.
    • Fig. S2. Photoactivation of the bouton/node with targeted ChR2 uncaging leads to significant spike narrowing.
    • Fig. S3. Determining parameters of IbTx application for local BK channel inhibition.
    • Fig. S4. Mimicking spike-evoked Ca2+ rises in distal AIS with targeted Ca2+ uncaging.
    • Fig. S5. Ca2+ uncaging at the bouton leads to significant spike narrowing in 4AP perfused neurons.

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