Science Advances

Supplementary Materials

This PDF file includes:

  • Fig. S1. DMI of 6,6′-2H2glucose and 2H3acetate metabolism.
  • Fig. S2. High-resolution 1H NMR of rat plasma.
  • Fig. S3. DMI detects the effect of DCA on glucose metabolism.
  • Fig. S4. Difference in 2H-acetate metabolism between normal-appearing rat brain and tumor tissue.
  • Fig. S5. In vivo 2H MRSI spectra from human brain.
  • Fig. S6. DMI of the Warburg effect in a patient with GBM.
  • Fig. S7. High-resolution 13C NMR spectra of 13C- and 2H-labeled lactate in cell culture medium.
  • Table S1. T1 and T2 relaxation times.
  • Table S2. T2* of water from the brain in vivo at 4 and 11.7 T.

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