Science Advances

Supplementary Materials

This PDF file includes:

  • Section S1. Model development
  • Section S2. Sensitivity analysis
  • Fig. S1. Collective antibiotic tolerance.
  • Fig. S2. Varying exogenous Bla.
  • Fig. S3. Time course and rate of change curves of isolate I.
  • Fig. S4. Time courses and rate of change curves generated by the model.
  • Fig. S5. Quantifying Bla activity in different components of culture.
  • Fig. S6. Sensitivity analysis reveals parameters affecting resistance and resilience.
  • Fig. S7. Time courses showing the effects of Bla inhibition.
  • Fig. S8. Framework can be applied to heterogeneous populations.
  • Fig. S9. Schematic for methods.
  • Table S1. ESBL-producing isolates screened.
  • References (4252)

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