Science Advances

Supplementary Materials

The PDF file includes:

  • Supplementary Materials and Methods
  • Fig. S1. Neuroblast migration in the 18-day poststroke brain.
  • Fig. S2. Impaired neuroblast migration by Slit-Robo signaling inhibition.
  • Fig. S3. Neuroblast-induced cytoskeletal modification in reactive astrocytes.
  • Fig. S4. Effects of Slit1 overexpression on the migration, proliferation, and apoptosis of neuroblasts.
  • Legends for movies S1 to S7
  • References (59, 60)

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Other Supplementary Material for this manuscript includes the following:

  • Movie S1 (.mov format). SBF-SEM and 3D-reconstructed images of migrating neuroblasts and surrounding astrocytes in the poststroke brain.
  • Movie S2 (.mov format). Time-lapse imaging of migrating neuroblasts and reactive astrocytes in a poststroke brain slice.
  • Movie S3 (.mov format). Time-lapse imaging of neuroblasts migrating in a reactive astrocyte–enriched area in poststroke brain slices.
  • Movie S4 (.mov format). Altered actin polymerization in astrocytes making contact with migrating neuroblasts.
  • Movie S5 (.mp4 format). Alteration in Cdc42 activity in astrocytes induced by neuroblast contact.
  • Movie S6 (.mov format). Dynamic alteration of Cdc42 activity and protrusion formation at the surface of astrocytes.
  • Movie S7 (.mov format). Time-lapse imaging of Cnt and Slit1-OE neuroblasts in the poststroke brain.

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