Science Advances

Supplementary Materials

This PDF file includes:

  • Fig. S1. Schematics of the reporter genes.
  • Fig. S2. Detection of single RNAs and measurement of transcription rates.
  • Fig. S3. I–Sce I cleaves the reporter genes driving MDC1 recruitment to damaged loci.
  • Fig. S4. Single-molecule calibration measurements.
  • Fig. S5. Single transcript calibration measurements.
  • Fig. S6. Break-induced nucleosome depletion.
  • Table S1. Sequence of primers used in this study.

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