Science Advances

Supplementary Materials

This PDF file includes:

  • Fig. S1. Gut microbial composition differences between patients with SCZ and HC subjects.
  • Fig. S2. Impact of confounding variables on global gut microbial phenotypes.
  • Fig. S3. Comparison of microbial markers between patients with SCZ and major depressive disorder.
  • Fig. S4. Comparison of gut microbial characteristics between SCZ microbiota and HC microbiota recipient mice.
  • Fig. S5. Metabolomic analysis of fecal, serum, and hippocampal samples obtained from SCZ microbiota and HC microbiota recipient mice.
  • Fig. S6. IPA shows that differentially expressed fecal, serum, and hippocampus metabolites were consistently involved in amino acid metabolism, especially glutamate metabolism.
  • Fig. S7. Levels of glutamine, glutamic acid, and GABA in SCZ microbiota and HC microbiota recipient mice.
  • Table S1. Detailed clinical characteristics of participants.
  • Table S2A. Discriminatory OTUs between patients with SCZ and HC subjects.
  • Table S2B. Discriminatory KEGG pathways between SCZ microbiota and HC microbiota recipient mice.
  • Table S3A. Differential fecal metabolites between SCZ microbiota and HC microbiota recipient mice.
  • Table S3B. Differential serum metabolites between SCZ microbiota and HC microbiota recipient mice.
  • Table S3C. Differential hippocampus metabolites between SCZ microbiota and HC microbiota recipient mice.

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Correction (21 June 2019): The last column on the ID: ko00532 line in table S2B, in the Supplementary Materials, incorrectly displayed "Down" instead of "Up".

The original version is accessible here.

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