Science Advances

Supplementary Materials

The PDF file includes:

  • Fig. S1. Design and construction of the DNA nanoswitch.
  • Fig. S2. Programmable design of the DNA nanoswitch.
  • Fig. S3. Concept validation using miRNA let-7b.
  • Fig. S4. Specificity and sensitivity in other miRNAs.
  • Fig. S5. Mismatch detection in small RNA samples.
  • Fig. S6. Protocol modification for total RNA detection.
  • Fig. S7. Sensitivity of miR-206 detection from RNA extracts.
  • Fig. S8. MicroRNA detection in different cell lines.
  • Fig. S9. Stability of the nanoswitch after drying.
  • Table S1. Comparison of miRacles assay with currently existing miRNA detection methods.

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Other Supplementary Material for this manuscript includes the following:

  • Movie S1 (.mov format). Time-lapse movie of miRNA detection in 1 hour using miRacles assay.

Files in this Data Supplement: