Science Advances

Supplementary Materials

The PDF file includes:

  • Fig. S1. Schematics of Neurotassel fabrication steps.
  • Fig. S2. 61-channel Neurotassels.
  • Fig. S3. Flip chip–bonded 16- and 61-channel Neurotassels.
  • Fig. S4. Simulated deformation and von Mises stresses in Neurotassels.
  • Fig. S5. Elastocapillary assembly of Neurotassels with water and PEG.
  • Fig. S6. Implantation of Neurotassel/PEG composite fiber in brain phantom.
  • Fig. S7. Simultaneous recordings from aPC and pPC by two Neurotassels.
  • Fig. S8. Time-dependent analysis of all recorded spiking activities during behavior training.
  • Fig. S9. Time-dependent analysis of the spiking activities of two example neurons during behavioral training.
  • Fig. S10. Simultaneous optical stimulation and electrical recordings with Neurotassel/optical fiber dual-functional probes.
  • Fig. S11. Long-term recording stability of Neurotassels.
  • Fig. S12. Chronic tissue response of Neurotassel and silicon probe after 5-week implantation.
  • Fig. S13. Chronic tissue response of implanted probes.
  • Fig. S14. Microglial activation in response to chronically implanted Neurotassel and silicon probe.
  • Fig. S15. High-density Neurotassels.
  • Fig. S16. Recordings with 1024-channel Neurotassels.
  • Legends for movies S1 to S6
  • Reference (60)

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Other Supplementary Material for this manuscript includes the following:

  • Movie S1 (.mov format). Released Neurotassel.
  • Movie S2 (.mov format). Elastocapillary assembly of Neurotassel.
  • Movie S3 (.mov format). Depth implantation of Neurotassel in brain.
  • Movie S4 (.mov format). Dissolution of PEG of Neurotassel/PEG fiber in the brain.
  • Movie S5 (.mov format). Simultaneous optogenetic stimulation and recording with assembled Neurotassel/optical fiber probe.
  • Movie S6 (.mov format). Mice with chronically implanted Neurotassels.

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