Science Advances

Supplementary Materials

The PDF file includes:

  • Fig. S1. USP1 regulates the response to CDDP in OC cells.
  • Fig. S2. USP1 binds and regulates Snail protein stability in control and CDDP-treated cells.
  • Fig. S3. Snail coordinates the USP1-mediated effects on CDDP-induced cell death and stem-like properties.
  • Fig. S4. USP1 is phosphorylated by ATM and ATR kinases on S42 and S331.
  • Fig. S5. USP1 is necessary for metastatic dissemination of OC cells.
  • Fig. S6. High USP1 expression predicts poor prognosis in patients with OC and is associated with acquired CDDP resistance.
  • Fig. S7. High USP1 expression predicts poor prognosis in patients with TNBC.

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Other Supplementary Material for this manuscript includes the following:

  • Table S1 (Microsoft Excel format). Identification and quantification of USP1 phosphorylated peptides.
  • Table S2 (Microsoft Excel format). Genes differentially expressed in responder versus nonresponder cells.
  • Table S3 (.pdf format). KEGG pathways by the DAVID Bioinformatics tool in responder versus nonresponder cells.

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