Science Advances

Supplementary Materials

The PDF file includes:

  • Fig. S1. SETDB1 telomeric binding is developmentally regulated.
  • Fig. S2. HP1α stimulates SETDB1-dependent heterochromatin formation at telomeres.
  • Fig. S3. ATRX binds heterochromatic telomeres.
  • Fig. S4. Telomeric heterochromatin stimulates transcriptional elongation.
  • Fig. S5. SETDB1-dependent heterochromatin promotes the recruitment of recombination factors and the appearance of ALT features.
  • Fig. S6. ATRX prevents recombination when telomeres are heterochromatic.
  • Fig. S7. Loss of SETDB1 and not of SUV39H promotes ALT features.
  • Fig. S8. Full membranes from which ChIP figures were prepared.
  • Legends for tables S1 and S2

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Other Supplementary Material for this manuscript includes the following:

  • Table S1 (Microsoft Excel format). List of factors enriched in the telomere PICh performed with wild-type ESCs.
  • Table S2 (Microsoft Excel format). List of factors enriched in the telomere PICh performed with wild-type mouse embryonic fibroblast cells.

Files in this Data Supplement: