Science Advances

The PDF file includes:

• Fig. S1. Optical system for imaging and closing mouse ear blood vessels.
• Fig. S2. In vivo confocal Raman spectra of blood cells, sebaceous gland, and collagen.
• Fig. S3. Schematic of the point treatment system.
• Table S1. Tentative assignment of Raman bands.

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Other Supplementary Material for this manuscript includes the following:

• Movie S1 (.avi format). Y-shaped blood vessels before closure of the vertical blood vessel.
• Movie S2 (.avi format). V-shaped blood vessel after closure of the vertical blood vessel.
• Movie S3 (.avi format). Three-dimensional orientation of two blood vessels before treatment.
• Movie S4 (.avi format). Three-dimensional orientation of two blood vessels after treatment.
• Movie S5 (.avi format). fsRCM of the blood vessel during the fs laser treatment.
• Movie S6 (.avi format). The dynamic process of the blood vessel closure using the point treatment system.
• Movie S7 (.avi format). Partial closure of blood vessel.