Science Advances

Supplementary Materials

This PDF file includes:

  • Fig. S1. PES1 specifically interacts with hTERT.
  • Fig. S2. PES1 forms a complex with hTERT and hTR.
  • Fig. S3. Identification of PES1 KO MCF7 cell line and PES1 KO mice.
  • Fig. S4. PES1 modulates telomerase activity and telomere length.
  • Fig. S5. PES1 modulates telomere length.
  • Fig. S6. PES1 KD induces cellular senescence.
  • Fig. S7. Effects of PES1 on modulation of noncanonical functions of TERT.
  • Table S1. siRNAs and shRNAs for PES1 and hTERT.
  • Table S2. Optimized coding sequence of hTERT.

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