Science Advances

Supplementary Materials

The PDF file includes:

  • Fig. S1. TLR2 expression is induced during OIS in vitro.
  • Fig. S2. TLR2 expression is induced during OIS in vivo.
  • Fig. S3. TLR2 and TLR10 regulate the SASP in OIS.
  • Fig. S4. TLR2 reinforces the cell cycle arrest in OIS.
  • Fig. S5. TLR2 and TLR10 regulate the activation of genes of the acute-phase response during OIS.
  • Fig. S6. A-SAA signaling through TLR2 controls the SASP.
  • Fig. S7. tlr2 is necessary for OIS activation in vivo.
  • Table S1. Primers used for qRT-PCR in this study.
  • Table S2. siRNA sequences used in this study.
  • Table S3. Antibodies used in this study.

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Other Supplementary Material for this manuscript includes the following:

  • Data file S1 (Microsoft Excel format). Transcriptome analysis of the effect of TLR2 and TLR10 siRNAs in OIS.
  • Data file S2 (Microsoft Excel format). Genes coregulated by TLR2 and TLR10 in OIS.
  • Data file S3 (Microsoft Excel format). Genes regulated only by TLR10 in OIS.

Files in this Data Supplement: