Science Advances

Supplementary Materials

This PDF file includes:

  • Fig. S1. 1H NMR spectrum of TMAO monomer.
  • Fig. S2. HRMS spectrum of TMAO monomer.
  • Fig. S3. Cell adhesion test.
  • Fig. S4. GPC graph of KLH, PEG10k-KLH, and TMAO-KLH conjugates.
  • Fig. S5. GPC graph of native uricase, PEG10k-uricase, and TMAO-uricase conjugates.
  • Fig. S6. Protein stability test.
  • Table S1. Circulation time of uricase samples after repeated intravenous injections.

Download PDF

Files in this Data Supplement: