Science Advances

Supplementary Materials

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  • Table S1. Summary of the MD simulations carried out on the C-terminal domain of Sendai virus and discussed in the present work.
  • Table S2. Summary of the results of the ABSURD procedure.
  • Fig. S1. Experimental secondary chemical shifts (bars) compared with values calculated using frames extracted from the trajectories every 500 ps as input to SPARTA+.
  • Fig. S2. Distribution of radii of gyration in the ensemble used to seed the MD simulations (bars) compared with those calculated using frames extracted from the trajectories every 200 ps.
  • Fig. S3. Experimental 15N chemical shift anisotropy/dipole-dipole cross-correlated cross-relaxation rates (ηxy) measured on Ntail compared with the results of simulations.
  • Fig. S4. Root-mean-square deviations between experimental and simulated spin relaxation rates at 298K.
  • Fig. S5. Root-mean-square deviations between experimental and simulated spin relaxation rates at 288K.
  • Fig. S6. Root-mean-square deviations between experimental and simulated spin relaxation rates at 278K.
  • Fig. S7. Time scales in the correlation function describing the contribution of backbone dihedral angles dynamics to relaxation of 15N backbone amide nuclei.
  • Fig. S8. Time scales in the correlation function describing the contribution of segmental motions to relaxation of 15N backbone amide nuclei.
  • Fig. S9. Fluctuations of the relative orientation of peptide planes measured by the order parameter S2seg.
  • Fig. S10. Time scales extracted from fits of correlation functions describing the rotational dynamics of segments to mono-exponential decays.
  • Fig. S11. Time scales associated with intra-segment dynamics at 288K (orange circles) are compared with the longest time scale resulted from fitting segmental dynamics correlation functions (gray squares).
  • Fig. S12. Time scales associated with intra-segment dynamics at 278K (yellow circles) are compared with the longest time scale resulted from fitting segmental dynamics correlation functions (gray squares).
  • Reference (61)

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