Science Advances

Supplementary Materials

The PDF file includes:

  • Fig. S1. JAZF1-SUZ12 is a molecular bridge between NuA4 and PRC2.
  • Fig. S2. CATACOMB is a eutherian-specific gene.
  • Fig. S3. CATACOMB M406I/A and two deletion mutants retain the ability to reduce H3K27me2/3 levels in the cells.
  • Fig. S4. CATACOMB expression in different cells is achieved by different demethylating agent treatment regimen.
  • Fig. S5. H3K27me3 is present in U2OS and increases upon CATACOMB KO.
  • Legend for table S1

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Other Supplementary Material for this manuscript includes the following:

  • Table S1 (Microsoft Excel format). FLAG-IP mass spectrometry results from hEnSC, expressing JAZF1-SUZ12 fusion, SUZ12 full length, or JAZF1 full length.

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