Science Advances

Supplementary Materials

The PDF file includes:

  • Fig. S1 Elp123 cryo-EM reconstruction.
  • Fig. S2. Atomic structure of the Elp1 N terminus and intersubunit contacts.
  • Fig. S3. Structural comparison of individual Elongator subunits.
  • Fig. S4. Cryo-EM reconstruction of Elp123-tRNA.
  • Fig. S5. Cryo-EM reconstruction of Elp123 bound to two tRNAs.
  • Fig. S6. In vivo and in vitro characterization of Elongator mutants.
  • Table S1. Collection and refinement statistics.
  • Table S2. Yeast strains used in this study.

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Other Supplementary Material for this manuscript includes the following:

  • Movie S1 (.mp4 format). Conformational changes of Elp123 upon tRNA binding.

Files in this Data Supplement: