Science Advances

Supplementary Materials

The PDF file includes:

  • Supplementary Materials and Methods
  • Fig. S1. Distinct enhancer-binding of CEBPA in WT GMPs versus p30 L-GMPs, related to Fig. 1.
  • Fig. S2. Motif enrichment analysis of p42, common and p30 CEBPA-bound regions, related to Fig. 2.
  • Fig. S3. Gene expression analysis of murine and human CEBPA mutant AML, related to Fig. 3.
  • Fig. S4. CEBPA-p30 directly activates the expression of Nt5e, related to Fig. 4.
  • Fig. S5. CD73-positive GMPs in human AML and CBF-MYH binding of the NT5E promoter in INV(16) AML, related to Fig. 5.
  • Fig. S6. A2AR-dependent adenosinergic autocrine survival signaling promoted by CD73, related to Fig. 6.
  • Legends for data files S1 to S7.
  • References (5273).

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Other Supplementary Material for this manuscript includes the following:

  • Data file S1 (Microsoft Excel format). CEBPA-peak coordinates, enriched motifs in CEBPA regions, related to Fig. 1.
  • Data file S2 (Microsoft Excel format). RNA-seq data, related to Figs. 2 and 3.
  • Data file S3 (Microsoft Excel format). MS data, related to Figs. 2 and 3.
  • Data file S4 (Microsoft Excel format). Gene signatures, related to Fig. 3.
  • Data file S5 (Microsoft Excel format). RNA-seq data, related to Fig. 6.
  • Data file S6 (Microsoft Excel format). Gene signatures, related to Fig. 6.
  • Data file S7 (Microsoft Excel format). Materials lists, related to Materials and Methods.

Files in this Data Supplement: