Science Advances

Supplementary Materials

This PDF file includes:

  • Scheme S1. Synthesis route of polymers.
  • Fig. S1. Characterization of the complex.
  • Fig. S2. 1H NMR spectra of various compounds synthesized.
  • Fig. S3. In vitro insulin release studies.
  • Fig. S4. Evaluation of insulin complexes in type 1 diabetic mice.
  • Fig. S5. Host response and toxicity evaluation in diabetic mice.
  • Fig. S6. The Masson’s trichrome staining sections of the skin with or without treatment.
  • Fig. S7. The immunofluorescence staining sections of the skin with or without treatment.
  • Fig. S8 Characterization of MN array patch.
  • Fig. S9. Glucose challenge study in diabetic minipigs.
  • Table S1. The BGLs of diabetic pigs.

Download PDF

Files in this Data Supplement: