Science Advances

Supplementary Materials

This PDF file includes:

  • Fig. S1. Activation of immune response by gluten peptides.
  • Fig. S2. Effects of HLA genotype and previous gluten exposure on cytokine response and cytokine response stratified by Nausea scores or occurrence of vomiting.
  • Fig. S3. Cytokine release assessed in plasma and serum.
  • Fig. S4. Gating strategy for the generation of primary human CD4+ T cell lines.
  • Fig. S5. Cytokine release in gluten-specific CD4+ T cell clones and short-term CD4+ T cell lines.
  • Fig. S6. Cytokine release in gluten-specific CD4+ T cell clones, short-term CD4+ T cell lines, and antigen-presenting cells.
  • Fig. S7. Cytokine release in fresh whole blood incubated with Nexvax2 peptides for 24 hours.
  • Table S1. Plasma cytokines after intradermal Nexvax2 assessed with 38-plex magnetic bead assay.
  • Table S2. Plasma cytokines after intradermal Nexvax2 assessed with 18-plex ECL assay.
  • Table S3. Characteristics of patients enrolled in masked, 3-gram gluten food challenge study.

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