Science Advances

Supplementary Materials

This PDF file includes:

  • Fig. S1. Loss of Ant1/2/4 genes in the liver does not compromise mitochondrial energetics or cause tissue pathology.
  • Fig. S2. Adenine nucleotide levels and transport in liver and MEF mitochondria lacking ANT proteins.
  • Fig. S3. Mitochondria from quadruple null mice fail to undergo Ca2+-induced MPTP, although no defects in energetics or mitochondrial ultrastructure were observed.
  • Fig. S4. Model of the MPTP.

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