Science Advances

Supplementary Materials

This PDF file includes:

  • Fig. S1. Effects of BMP-2–primed engineered mesenchymal condensations and routine clinical therapies on new bone quantity and architecture in the absence of mechanical cues.
  • Fig. S2. Effects of morselized autografts and in vivo mechanical loading on longitudinal bone formation and bone accumulation rate.
  • Fig. S3. Effects of morphogen priming of engineered mesenchymal condensations and in vivo mechanical loading on defect bridging.
  • Fig. S4. Effects of morphogen priming of engineered mesenchymal condensations and in vivo mechanical loading on new bone distribution and architecture.
  • Fig. S5. Best subset analysis of mechanical testing data.
  • Fig. S6. Effects of morphogen priming of engineered mesenchymal condensations on in vitro chondrogenic lineage specification at the time of implantation.
  • Fig. S7. Effects of morphogen priming of engineered mesenchymal condensations and in vivo mechanical loading on tissue-level bone regeneration at 4 weeks.
  • Fig. S8. Effects of morphogen priming of engineered mesenchymal condensations and in vivo mechanical loading on tissue-level bone regeneration at 12 weeks.
  • Table S1. Oligonucleotide primer sequences for qRT-PCR.

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