Science Advances

Supplementary Materials

The PDF file includes:

  • Fig. S1. Full infection matrix highlights coevolutionary phenotypic changes.
  • Fig. S2. Resistance is costly.
  • Fig. S3. Genetic diversity after selective sweeps matches expectations under neutrality.
  • Fig. S4. Repeatable genomic change provides evidence for the action of natural selection.
  • Fig. S5. Ecological change is less dynamic in the absence of species interactions.
  • Table S1. Sequencing and filtering statistics indicate the reliability of the genomic datasets.
  • Table S2. Observing mutations in multiple replicates independently is unlikely under neutrality.
  • Table S3. Functional annotations of SNPs at high frequency in host populations after selective sweep at day 27.
  • Table S4. Functional annotations of SNPs at high frequency in host populations after selective sweep at day 64.
  • Legends for data files S1 to S3

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Other Supplementary Material for this manuscript includes the following:

  • Data file S1 (.csv format). Population sizes (observed and smoothed values).
  • Data file S2 (.csv format). Results of phenotypic assays.
  • Data file S3 (.csv format). Filtered derived allele frequencies.

Files in this Data Supplement: