Science Advances

Supplementary Materials

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  • Fig. S1. The expression of the endothelial cell marker CD31 in hBMECs.
  • Fig. S2. Infection with both SZ01 and PRVABC59 only induces a slightly cytopathic effect at a high dose.
  • Fig. S3. The relative protein densities of Western blot in Fig. 1.
  • Fig. S4. ZIKV infection down-regulates Mfsd2a expression in JEG-3 cells.
  • Fig. S5. ZIKV infection down-regulates Mfsd2a expression in vivo.
  • Fig. S6. The degradation of Mfsd2a by ZIKV E can be inhibited by MG132.
  • Fig. S7. Mfsd2a-overexpressing cells show a strong uptake of TopFluor-LPC.
  • Table S1. Phospholipid species in mock- or ZIKV-infected hBMECs, related to Fig. 5A.
  • Table S2. Phospholipid species in mock- or ZIKV-infected neonatal mouse brains, related to Fig. 5C.

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