Science Advances

Supplementary Materials

The PDFset includes:

  • Fig. S1. Distribution of selection coefficients in the computer simulations of evolving populations.
  • Fig. S2. Growth curves in ewe milk.
  • Legends for tables S1 and S2.
  • Table S3. Remaining mutations acquired during the infections and passages.
  • Table S4. Coinfection experiment results.
  • Table S5. Coinfection experiment results with isogenic strains.
  • Table S6. SNP fixed in the population at different times.
  • Table S7. Counts of the SNP found in 3% of the population.
  • Table S8. Bacterial strains, plasmids, and oligonucleotides used in this study.

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Other Supplementary Material for this manuscript includes the following:

  • Table S1 (Microsoft Excel format). Detailed transmission chains of the infections.
  • Table S2 (Microsoft Excel format). Information on the isolates used in this study.

Files in this Data Supplement: