Science Advances

Supplementary Materials

The PDFset includes:

  • Fig. S1. Metagenomic characterization of 1163 samples from 160 premature infants.
  • Fig. S2. Fecal samples taken before NEC diagnosis have a higher abundance of plasmids from specific bacterial taxa.
  • Fig. S3. PCA is unable to separate pre-NEC and control samples.
  • Fig. S4. ML feature importance values reveal organismal associations with NEC.
  • Legends for tables S1 to S6

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Other Supplementary Material for this manuscript includes the following:

  • Table S1 (.csv format). Metagenomic sequencing depth and read quality information.
  • Table S2 (Microsoft Excel format). Patient metadata.
  • Table S3 (Microsoft Excel format). Information about dereplicated secondary metabolite clusters, de novo‚Äďassembled genomes, and genome-wide importances of genomes.
  • Table S4 (Microsoft Excel format). Accuracy of ML algorithms and protein clustering algorithms and mapping-based abundances of bacterial taxa.
  • Table S5 (Microsoft Excel format). Full feature table provided to the ML classifier and importances of all features resulting from the ML classifier.
  • Table S6 (Microsoft Excel format). Proteins enriched in genomes of interest and identified fimbrial genes.

Files in this Data Supplement: