Science Advances

Supplementary Materials

This PDF file includes:

  • Fig. S1. Differentially expressed lncRNAs in LPS- and IL-4–stimulated BMDMs.
  • Fig. S2. PTPRE-AS1 mediates PTPRE expression.
  • Fig. S3. Neither PTPRE-AS1 nor PTPRE influences IL-4–induced STAT6 phosphorylation levels.
  • Fig. S4. Generation of PTPRE-AS1 KO mice.
  • Fig. S5. PTPRE-AS1 and PTPRE are reduced in both DSS-induced colitis and CRE-induced allergic asthma.
  • Fig. S6. PTPRE-AS1 inhibits the expression of M2 macrophage–associated genes in THP1 macrophages.
  • Fig. S7. PTPRE-AS1 deficiency promotes the proliferation and expansion of lung resident macrophages stimulated by IL-4.
  • Table S1. Demographic and respiratory health characteristics of patients with allergic asthmatic and healthy controls.
  • Table S2. The primer sequences.
  • Table S3. The sequences of PTPRE-AS1 ASO, shRNA, PTPRE siRNA, and WDR5 siRNA.

Download PDF

Files in this Data Supplement: