Science Advances

This PDF file includes:

• Fig. S1. Illustration of the fabricated microfiber device.
• Fig. S2. The measured transmission spectrum of silica microfiber.
• Fig. S3. The simulated modal distributions of silica microfiber and microfiber with BP spacer.
• Fig. S4. Optical stabilities of the microfiber sensors in PBS solution.
• Fig. S5. Wavelength shifts recorded by the control microfiber when target molecules were added in its side.
• Fig. S6. Optical response with respect to time by using microfiber functionalized by Au nanohybrids without BP spacer in BSA solution and IgG solution at a concentration of 1 aM.
• Fig. S7. Wavelength shift of the microfiber with BP-supported Au nanohybrid interface under pump laser coupling and the wavelength shift of the microfiber versus temperature increase.
• Fig. S8. The AFM images of the microfiber functionalized with different nanointerfaces.
• Fig. S9. HR-TEM image of Au nanohybrids and near-field intensity of electrical field on different nanointerfaces.

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