Science Advances

The PDFset includes:

• Fig. S1. Optimizing the screen.
• Fig. S2. Mitotoxicity and neurotoxicity with FCCP treatment.
• Fig. S3. False-positive hit rate in the screen.
• Fig. S4. Structural clustering of the MnMs.
• Fig. S5. Dose response of Aβ(1–42) oligomers, peroxide, and glutamate treatment on neuronal mitochondrial features.
• Fig. S6. Scheme of field outlier removal and using neutral wells for robust Z-score calculation.
• Table S1. The effect of MnMs on neurite sprouting.
• Table S2. EC₅₀ values of selected MnMs for processes of mitostasis and neurite sprouting.
• Legend for movie S1

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Other Supplementary Material for this manuscript includes the following:

• Movie S1 (.mov format). Time-lapse video of elongating and fusing mitochondria.