Science Advances

Supplementary Materials

The PDFset includes:

  • Supplementary Methods
  • Table S1. Summary of final multivariable logistic regression model.
  • Table S2. Summary of genome-wide significant SNPs following distance-based clumping on the UKB cohort, and the replication cohort and meta-analysis outcomes.
  • Legend for table S3
  • Table S4. LD between the top eQTL SNP for any eQTL signal and the GWAS SNP.
  • Table S5. Variant-trait significant outcomes from PheWAS.
  • Table S6. Variants at 5 × 10−6 and submitted to the Reactome Knowledgebase.
  • Table S7. Mendelian randomization results for nominally significant outcomes in the IVW analysis and FDR outcomes using the IVW method.
  • Fig. S1. LocusZoom plots for lead SNPs from GWAS on alcohol phenotype in the entire cohort.
  • Fig. S2. Constitutive signaling by aberrant PI3K in cancer.
  • Fig. S3. Individual C. elegans β-Klotho genes outcomes.
  • References (6171)

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Other Supplementary Material for this manuscript includes the following:

  • Table S3 (.csv format). eQTL analysis outcomes.

Files in this Data Supplement: