Science Advances

Supplementary Materials

The PDFset includes:

  • Fig. S1. CRISPR-Cas9 gene modification strategy is outlined.
  • Fig. S2. The SNP in PBANKA_011210 ApiAP2 TF does not interfere with the progression of sexual and pre-erythrocytic stages of the P. berghei life cycle.
  • Fig. S3. Flow cytometry gating strategy.
  • Fig. S4. Graphs comparing mice infected with PbNK65F and PbNK65S.
  • Table S1. Summary of changes observed between the WT and CRISPR-Cas9–mutated parasites based on whole-genome sequencing analysis.
  • Supplementary information 2. The 900-nucleotide synthetic sequence.

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Other Supplementary Material for this manuscript includes the following:

  • Data file S1 (.csv format). Supplementary information 1: DNA binding analysis of ApiAP2 domain 1.

Files in this Data Supplement: