Science Advances

Supplementary Materials

This PDF file includes:

  • Supplementary Materials and Methods
  • Fig. S1. Gevokizumab modification.
  • Fig. S2. TEM characterization of IL1-PM.
  • Fig. S3. Arming of Gevokizumab onto platelets.
  • Fig. S4. Confirming antibody conjugation and detoxification rate.
  • Fig. S5. Platelet markers on IL1-PM.
  • Fig. S6. Inactivated platelet microparticles can bind to damaged vasculatures.
  • Fig. S7. Circulation lifetime of IL1-PM in normal mice.
  • Fig. S8. Toxicity of IL1-PM treatment and quantification of IL-1β and IL-6 concentrations in the heart.
  • Fig. S9. Inflammatory response after treatments.

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