Science Advances

Supplementary Materials

This PDF file includes:

  • Fig. S1. Adolescent female mice carrying the FAAH SNP demonstrate no change in CB1R-labeled terminals forming symmetric or asymmetric synapses in the parabrachial subregion of the VTA.
  • Fig. S2. THC CPP dose response in adolescent female mice carrying the FAAH SNP.
  • Fig. S3. Adolescent and adult FAAHC/C and FAAHC/A mice show preference for cocaine CPP.
  • Fig. S4. Pharmacological inhibition of FAAH in WT mice is not sufficient to reproduce rewarding effect of THC seen in adolescent female mice with the FAAH SNP.
  • Fig. S5. THC CPP during adulthood does not result in a preference for THC in female mice carrying the FAAH SNP.

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