Science Advances

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• Fig. S1. FGL2 deficiency has no significant effect on both fibrin deposition in the spleen and coagulation function of the parasite-infected mice.
• Fig. S2. sFGL2 has no effect on parasite-specific antibody production.
• Fig. S3. sFGL2 has no effect on parasite-specific CD4⁺ T cell activation.
• Fig. S4. sFGL2 has no effect on parasite-specific CD8⁺ T cell activation.
• Fig. S5. Full blots of the effect of rFGL2 administration on both mitogen-activated protein kinase and NF-κB activity in P. chabaudi lysate–stimulated macrophages by rFGL2.
• Fig. S6. Full blots of the FcγRIIB-dependent inhibition of JNK in P. chabaudi lysate–activated macrophages by sFGL2.
• Fig. S7. Full blots of the inhibition of JNK in P. falciparum lysate–activated macrophages by rFGL2.
• Table S1. Detailed information of patients with malaria.

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