Science Advances

Supplementary Materials

The PDF file includes:

  • Fig. S1. CV-induced ISG15/ISGylation and its impact on virus load.
  • Fig. S2. Influence of USP18 inactivation in the early phase of CV infection.
  • Fig. S3. Intact function of innate myeloid cells in ISG15−/− mice during CV infection.
  • Fig. S4. Generation of Ube1L−/− bone marrow chimeric mice.
  • Fig. S5. Impact of ISG15 on IFIT1 and IFIT3 protein expression.
  • Fig. S6. Hepatic glucose flux in dependence of blood glucose.
  • Fig. S7. Cell culture models to investigate the antiviral activity of human ISG15.
  • Fig. S8. Influence of ISG15 on experimental troponin I–induced AM.
  • Fig. S9. Analysis of mitochondrial respiration in wild-type and ISG15−/− hepatocytes.

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Other Supplementary Material for this manuscript includes the following:

  • Table S1 (Microsoft Excel format). MaxQuant data liver tissue.

Files in this Data Supplement: