Science Advances

Supplementary Materials

The PDF file includes:

  • Supplemental Methods
  • Fig. S1. Heat map of percent decrease in confluence and viability for bottom performing cell lines.
  • Fig. S2. Survival is maximized on collagen I coverslips.
  • Fig. S3. Serum-starved cells are cell cycle arrested and nonproliferative.
  • Fig. S4. Proteomic of ECM produced by HCC 1954 during serum starvation and recovery.
  • Fig. S5. Dormant cells organize fibronectin.
  • Fig. S6. Fibronectin is locally degraded during reactivation via MMPs.
  • Fig. S7. Integrin expression of dormant cells determined by quantitative polymerase chain reaction.
  • Fig. S8. ERK mediates survival in other cell lines.
  • Table S1. Inhibitors and activators used in experiments.
  • Table S2. Antibodies used for immunofluorescence.
  • Table S3. Integrin and CDKN primers.
  • Legend for movie S1
  • References (82, 83)

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Other Supplementary Material for this manuscript includes the following:

  • Movie S1 (.avi format). Rare cells divide after 4 weeks of serum-free culture.

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