Science Advances

Supplementary Materials

This PDF file includes:

  • Fig. S1. Schematic of the procedures for isolating EVs from conditioned cell culture medium.
  • Fig. S2. Characterization of EVs isolated from murine NSCLC cell lines.
  • Fig. S3. Gene Ontology analysis of proteins up-regulated or uniquely detected in EVs from 344SQ cells.
  • Fig. S4. Tspan8 enriched in EVs derived from A549ITSN2+ cells.
  • Fig. S5. Schematic of the procedures for analyzing the influence of EV-Tspan8 on cell metastasis.
  • Fig. S6. EV-Tspan8 induced invasion in a concentration-dependent manner.
  • Table S1. Patient and treatment characteristics.

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