Science Advances
Supplementary Materials
This PDF file includes:
- Supplementary Material and Methods
- Fig. S1. Compounds inhibit STAT3-dependent luciferase and covalently interact with GSH.
- Fig. S2. Whole gel images of competition experiments of
Fig. 3 . - Fig. S3. Whole gel images of competition experiments of
Fig. 3 . - Fig. S4. SDS-PAGE fluorescent band matches TrxR1 protein on Western blot.
- Fig. S5. CellTiter-Glo cell viability with or without selenium supplementation.
- Fig. S6. Whole blot images of Western blot replicates.
- Fig. S7. STAT-driven luciferase inhibition in Prx1 + Prx2 knockdown cells.
- Fig. S8. Catalase decreases H2O2 production affecting cell cytotoxicity of top DG compounds.
- Fig. S9. Compound effects on alternative transcription factors.
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